AZ3146 WP L6 VLX1570 has potent antiproliferative activities

VLX1570 has potent antiproliferative activities on multiple myeloma cells

SR10067 was used at 5-10 µM concentration in vitro and in cellular assays

is a potent and selective rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains

identified by a high-throughput

AZ3146 WP L6 VLX1570 has potent antiproliferative activitiesAZ3146 is a novel and potent Mps1 inhibitor, which was used to probe the role of Mps1's catalytic activity during mitosis. AZ3146 also inhibits FAK, JNK1, JNK2, KSP and Kit. In in vitro kinase assays, AZ3146 inhibited human Mps1Cat with an IC50 (50% inhibitory concentration) of ~35 nM. AZ3146 also efficiently inhibited autophosphorylation of full length Mps1 immunoprecipitated from human cells. Product information CAS Number: 1124329 14 1 Molecular