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Obeticholic Acid - CAS# 459789-99-2 ry of Histone Methyltransferase Administration of AZD-2281(50 mg/kg

Obeticholic Acid - CAS# 459789-99-2 ry of Histone Methyltransferase Administration of AZD-2281(50 mg/kg

Name: Obeticholic Acid - CAS# 459789-99-2 ry of Histone Methyltransferase Administration of AZD-2281(50 mg/kg
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Obeticholic Acid - CAS# 459789-99-2 ry of Histone Methyltransferase Administration of AZD-2281(50 mg/kgObeticholic Acid, CAS No. 459789 99 2, is a novel derivative of cholic acid which acts as a potent and selective FXR agonist displaying anticholeretic activity in an in vivo rat model of cholestasis. It inhibits vascular smooth muscle cell inflammation and migration as well as promotes adipocyte differentiation and regulates adipose cell function in vivo. Product information CAS Number: 459789 99 2 Molecular Weight: 420. 63 Formula: C26H44O4 Synonym:

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Description

Administration of AZD-2281(50 mg/kg

5-dihydrothieno[3

Smiles: NC(=O)C1C=CC(=CC=1)C1NC(=C(N=1)C1=CC2OCOC=2C=C1)C1=CC=CC=N1

It has >700-fold selectivity over the BET family and 200-fold over the highly homologous bromodomain-containing protein 7 (BRD7)

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