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SC-514 - CAS# 354812-17-2 Catalog No.:M6663-2 Expert Rev Anticancer Ther

SC-514 - CAS# 354812-17-2 Catalog No.:M6663-2 Expert Rev Anticancer Ther

Name: SC-514 - CAS# 354812-17-2 Catalog No.:M6663-2 Expert Rev Anticancer Ther
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SC-514 - CAS# 354812-17-2 Catalog No.:M6663-2 Expert Rev Anticancer TherSC 514, CAS No. 354812 17 2, is a selective and reversible inhibitor of IB kinase 2 (IKK2) that may target osteoclastogenesis. SC 514 dose dependently inhibits RANKL induced osteoclastogenesis and induced apoptosis and caspase 3 activation in RAW264. 7 cells. Targeting IKK by SC 514 may be a potential treatment for osteoclast related disorders such as osteoporosis and cancer induced bone loss. Product information CAS Number: 354812 17 2 Molecular

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Expert Rev Anticancer Ther

Ferrer-Torres D

InChi: InChI=1S/C19H19N7O3/c1-24-17-16(18(28)25(2)19(24)29)26(11-21-17)15(27)10-20-14-9-8-13(22-23-14)12-6-4-3-5-7-12/h3-9

33) was higher than that of buspirone (pKi

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