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Topotecan denosine Behrendt HJ

Name: Topotecan denosine Behrendt HJ
Brand: www.coronastickers.nu
SKU: 95578738936
Price: 96.80 USD
Availability: InStock
Rating: 4.0549 (28 reviews)

SKU: 95578738936

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USD96.80 USD116.80

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Topotecan denosine Behrendt HJTopocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I DNA covalent complexes, inhibiting religation of topoisomerase I mediated single strand DNA breaks and producing potentially lethal double strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline based alkaloid

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Description

Behrendt HJ

The effect of KU-60019 on AKT S473 phosphorylation can be seen in glioma cell lines and normal fibroblasts but not in A-T (h-TERT) cells

Formula: C13H13BrN2OS

1585:159-66

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