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Vinflunine tartrate Size:Solid 10 mg 57Dihydroxyflavone

SKU: 95834621591

4.5
EUR119.00 EUR149.00

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Vinflunine tartrate Size:Solid 10 mg 57DihydroxyflavoneVinflunine is a bi fluorinated derivative of the semi synthetic vinca alkaloid vinorelbine with antitubulin, antineoplastic, and antiangiogenic activities. Vinflunine inhibits tubulin assembly without any stablization of assembled microtubules at concentrations comparable to those of other vinca alkaloids such as vincristine, vinblastine and vinorelbine; this effect on microtubule dynamics results in cell cycle arrest in mitosis and apoptosis.

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Description

57Dihydroxyflavone

1056901-62-2

PF-04457845

At higher concentrations it is also an efficient inhibitor of serine/threonine protein kinases (IC50 of 10 to 30 nmol/L)

Vinflunine tartrate Size:Solid 10 mg 57DihydroxyflavoneVinflunine is a bi fluorinated derivative of the semi synthetic vinca alkaloid vinorelbine with antitubulin, antineoplastic, and antiangiogenic activities. Vinflunine inhibits tubulin assembly without any stablization of assembled microtubules at concentrations comparable to those of other vinca alkaloids such as vincristine, vinblastine and vinorelbine; this effect on microtubule dynamics results in cell cycle arrest in mitosis and apoptosis.

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