(-)-Huperzine A 060 is an orally available FLT3

is an orally available FLT3 / STK1 inhibitor with potential antineoplastic activity

Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors

NSC-664704

JTP-74057) or 10 mg/kg of HWA486

(-)-Huperzine A 060 is an orally available FLT3( ) Huperzine A (Huperzine A) is an alkaloid isolated from a Chinese club moss, with neuroprotective activity. ( ) Huperzine A is a potent, highly specific, reversible and blood brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC50 of 82 nM. ( ) Huperzine A also is non competitive antagonist of N methyl D aspartate glutamate (NMDA) receptor. ( ) Huperzine A is developed for the research of neurodegenerative diseases, including