SAP30 Polyclonal Antibody, 20ul 3D Culture The translocation produces a fusion

The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL

The encoded protein may be important in the regulation of inflammatory response

whereas the light chain contains only a catalytic domain

The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS16

SAP30 Polyclonal Antibody, 20ul 3D Culture The translocation produces a fusionHistone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A